CPA und CPA PLUS

Short Description

• CPA

  The overall goal of this project is to launch collaborative research and thereby initiate and establish a network for the coordinated optimisation of anti-infective drug use. The pharmacogenetic analyses planned will advance awareness of modern medical methods of patient diagnostics into the clinical context. They will investigate in which way/how and if specific genetic polymorphisms in drug metabolising enzymes existing in the population of sub-Saharan Africa may affect negatively drug exposure in patients, and thereby contribute to the spread of drug resistance. The project will foster international collaboration by enabling knowledge transfer within the area of appropriate drug use. Keeping in mind potential resource constraints, the e-learning will be tailored to guide healthcare professionals by encouraging the safe and appropriate use of anti-infective drug use in hospitals, thereby ultimately enhancing patient safety. The e-learning tool could be further adapted to other healthcare settings.

• CPA PLUS

  Scope expansion towards promoting sustainability and increased collaborative actions in the dissemination of research approaches.

  The CPA PLUS project is complementary to CPA. The project further strengthens regulatory research competence at/of the African research partner institutions by:

  • Initiating a collaborative BfArM-AiBST research project to investigate in greater depth relevant polymorphisms associated with drug side effects and drug resistance in countries of southern Africa.
  • Collaboratively increasing awareness of knowledge gaps by improving access to information to better understand unmet needs.
  • Fostering engagement through dissemination of research aims. The documentary film will be devoted to presenting work done under CPA and highlighting activities of collaborating institutions to substantiate all of the above.

  CPA is therefore creating/facilitating improved research capacities to support personalised pharmacotherapy as a means for counteracting the spread of disease and drug resistance.